Genetic Skin Disease

Stressing a structure-function approach, this multidisciplinary reference presents a detailed overview of the biological, chemical, physical, molecular and genetic tools and techniques utilized in the study of the skin barrier. It illustrates the impact of irritative skin reactions, as well as genetic and immune-mediated disease on hair and nail composition and formation.

A lavishly illustrated guide to almost 200 inherited diseases of the skin, hair, and nails. Each entry inlcudes synonyms, age of onset, clinical findings, complications, course, laboratory findings, diagnosis, therapy, and key references, adding up to far more than just a collection of photographs. In addition to being a clinical primer, this is also a work of scientific research and contains the first printed description of two new syndromes. The fast-moving world of genetic research means that the latest genetic correlations, included here, render previous texts out of date. All specialists in dermatology and pediatrics should find this an invaluable front-line resource in the clinic.

Darier's disease - Darier's disease is a genetic disorder discovered by a French dermatologist Ferdinand-Jean Darier. Darier's disease is known because of dark crusty patches on the skin, sometimes containing pus.

Keratosis pilaris - Keratosis pilaris (KP) is a very common genetic follicular disease that is manifested by the appearance of rough bumps on the skin and hence colloqually referred to as "chicken skin". Primarily, it appears on the back and outer sides of the upper arms, but can also occur on thighs and buttocks or any body part except glabrous skin (like the palms or soles of feet).

Permanent makeup - Permanent makeup is a cosmetic technique which employs tattoos (permanent pigmentation of the dermis) as a means of producing designs that resemble makeup, such as eyelining (eye shadows and mascara) and other permanent enhancing colors to the skin of the face, lips and eyelids. It is also used to produce artificial eyebrows, particulary in people who have lost it as a consequence of old age, disease, such as alopecia, chemotherapy or a genetic disturbance, and to disguise scars and white spots in the skin such as in vitiligo.

Genetic disorder - A genetic disorder, or genetic disease is a disease caused by abnormal expression of one or more genes in a person causing a clinical phenotype. There are a number of possible causes for genetic defects:

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